ACVR1C/ALK7 Protein (AA 21-113) (His tag)
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- Target See all ACVR1C/ALK7 (ACVR1C) Proteins
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-113
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ACVR1C/ALK7 protein is labelled with His tag.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ACVR1C Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM Tris, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Alternative Name
- ALK-7 (ACVR1C Products)
- Background
- ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
- Molecular Weight
- 11.9 kDa
- NCBI Accession
- NP_660302
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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