Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag) Protein

ACE2 Origin: Paguma larvata Source: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS
Catalog No. ABIN6952704
$512.00
Plus shipping costs $45.00 and $24.00 dry ice
50 μg ABIN6952704
50 μg ABIN6952704
local_shipping Shipping to: United States
Will be delivered in 5 Business Days
  • Target
    ACE2
    Protein Type
    Recombinant
    Origin
    Paguma larvata
    Source
    HEK-293 Cells
    • 24
    • 11
    • 6
    • 4
    • 2
    • 1
    Purification tag / Conjugate
    This ACE2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purpose
    Paguma larvata ACE2 / ACEH Protein, His Tag
    Sequence
    AA 18-740
    Characteristics
    Paguma larvata ACE2, His Tag (AC2-P5248) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Thr 740 (Accession # Q56NL1-1). Predicted N-terminus: His
    This protein carries a polyhistidine tag at the N-terminus.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    50 mM Tris, 150 mM NaCl, pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    The product MUST be stored at -70°C or lower upon receipt
    -70°C for 3 months under sterile conditions.
  • Target
    ACE2
    Synonyms
    ACEH, 2010305L05Rik, zgc:92514, angiotensin I converting enzyme 2, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, ACE2, Ace2, ace2
    Background
    Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
    Molecular Weight
    85.7 kDa
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
You are here:
help Support