CCR2 Protein (AA 1-42) (Fc Tag)
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- Target See all CCR2 Proteins
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-42
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCR2 with C-terminal human Fc tag
- Specificity
- CCR2 (Met1-Ala42) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCR2 Protein
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Chemokine (C-C Motif) Receptor 2 (CCR2) protein
CCR2 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLPCCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-360) (Active) protein-VLP (Biotin)CCR2 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, Func, SPR Active
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-55) protein (Fc Tag)CCR2 Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (GST tag)CCR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 1-42) protein (mFc Tag)CCR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- Alternative Name
- CCR2 (CCR2 Products)
- Background
- The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
- Molecular Weight
- predicted molecular mass of 31.0 kDa after removal of the signal peptide.The apparent molecular mass of CCR2-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P41597
- Pathways
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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