K-RAS Protein (AA 1-169) (His tag)
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- Target See all K-RAS (KRAS) Proteins
- K-RAS (KRAS) (GTPase Kras (KRAS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-169
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Origin
- Human
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Source
- Insect Cells
- Purification tag / Conjugate
- This K-RAS protein is labelled with His tag.
- Characteristics
- Human KRAS Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KRAS Protein
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GTPase Kras (KRAS) protein (His tag)
KRAS Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.
GTPase Kras (KRAS) (AA 1-189) protein (GST tag)KRAS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
GTPase Kras (KRAS) (AA 2-185) protein (mFc Tag)KRAS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
GTPase Kras (KRAS) (AA 1-185) protein (His tag)KRAS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
GTPase Kras (KRAS) (AA 2-185) protein (Fc Tag)KRAS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
GTPase Kras (KRAS) (AA 1-186) protein (His tag)KRAS Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
GTPase Kras (KRAS) (AA 2-185) protein (His tag)KRAS Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
GTPase Kras (KRAS) (AA 1-188) protein (GST tag)KRAS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
GTPase Kras (KRAS) (AA 16-125) protein (GST tag)KRAS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 0.5 M NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- K-RAS (KRAS) (GTPase Kras (KRAS))
- Alternative Name
- KRAS (KRAS Products)
- Target Type
- Viral Protein
- Background
- KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) gene is a proto-oncogene that encodes a small GTPase transductor protein called KRAS. KRAS is also known as Ki-Ras, c-K-ras and c-Ki-ras. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation, promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. RAS is one of the most frequently mutated oncogenes in human cancer but the frequency and distribution of RAS gene mutations are not uniform. In details, mutation of glycine 12 (G12) causes RAS activation by interfering with GAP binding and GAP-stimulated GTP hydrolysis. The reference shows the pathway may as a potential therapy targets.
- Molecular Weight
- 21.3 kDa
- NCBI Accession
- NP_004976
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