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ZNRF3 Protein (AA 56-219) (His tag)

ZNRF3 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7013661
$415.38
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  • Target See all ZNRF3 Proteins
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 56-219
    Origin
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ZNRF3 protein is labelled with His tag.
    Sequence
    AA 56-219
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Application Notes
    MALS verified
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Alternative Name
    ZNRF3 (ZNRF3 Products)
    Synonyms
    BK747E2.3 Protein, RNF203 Protein, AA591877 Protein, BC019575 Protein, Gm1167 Protein, zinc and ring finger 3 Protein, Znrf3 Protein, ZNRF3 Protein
    Background
    The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.
    Molecular Weight
    19.7 kDa
    NCBI Accession
    NP_001193927
    Pathways
    WNT Signaling
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