CD45 Protein (AA 26-577) (His tag)
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- Target See all CD45 (PTPRC) Proteins
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-577
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD45 protein is labelled with His tag.
- Characteristics
- Human CD45 / PTPRC protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) protein (His-Avi Tag)
PTPRC Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) protein (His-Avi Tag,Biotin)PTPRC Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 598-1304) protein (His tag)Crystallography grade PTPRC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) protein (His tag)Crystallography grade PTPRC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-564) protein (His tag)Crystallography grade PTPRC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 587-1291) protein (His tag)Crystallography grade PTPRC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-1291) protein (rho-1D4 tag)Crystallography grade PTPRC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-1304) protein (rho-1D4 tag)Crystallography grade PTPRC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1207-1304) protein (GST tag)PTPRC Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 390-570) protein (GST tag)PTPRC Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
- Alternative Name
- CD45 (PTPRC Products)
- Synonyms
- PTPRC Protein, si:dkeyp-47c5.1 Protein, B220 Protein, CD45 Protein, CD45R Protein, GP180 Protein, L-CA Protein, LCA Protein, LY5 Protein, T200 Protein, Cd45 Protein, Ly-5 Protein, Lyt-4 Protein, loc Protein, Lca Protein, RT7 Protein, cd45 Protein, protein tyrosine phosphatase, receptor type C Protein, protein tyrosine phosphatase, receptor type, C Protein, receptor-type tyrosine-protein phosphatase C Protein, PTPRC Protein, ptprc Protein, LOC100074271 Protein, Ptprc Protein
- Background
- CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
- Molecular Weight
- 62.8 kDa
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
