NPR3 Protein (Fc Tag)
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- Target See all NPR3 Proteins
- NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This NPR3 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human NPRC/NPR3 (C-Fc)
- Sequence
- Thr24-Glu481
- Characteristics
- Recombinant Human Atrial Natriuretic Peptide Receptor 3 is produced by our Mammalian expression system and the target gene encoding Thr24-Glu481 is expressed with a Fc tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))
- Alternative Name
- NPRC/NPR3 (NPR3 Products)
- Background
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Background: Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation.
Synonym: ANP-C, ANPR-C, NPR3, NPRC, NPR-C,ANPRC, C5orf23
- Molecular Weight
- 77.5 kDa
- UniProt
- P17342
- Pathways
- cAMP Metabolic Process
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