CAMK2A Protein (GST tag)
-
- Target See all CAMK2A Proteins
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CAMK2A protein is labelled with GST tag.
- Purpose
- Recombinant Human CAMK2A/CAMKA Protein (GST Tag)(Active)
- Sequence
- Met 1-His 478
- Characteristics
- A DNA sequence encoding the human CAMK2A isoform 2 (NP_741960.1) (Met 1-His 478) was fused with the GST tag at the N-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 160 nmol/min/mg using Autocamtide-2 synthetic peptide (KKALRRQETVDAL-amide) as substrate.
- Top Product
- Discover our top product CAMK2A Protein
-
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 1-478) protein (GST tag)
CAMK2A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CAMK2A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CAMK2A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 0.5 mM Reduced Glutathione, pH 8.0
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- Alternative Name
- CAMK2A/CAMKA (CAMK2A Products)
- Background
-
Background: Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily. CaM kinase II is thought to be an important mediator of learning and memory and is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.
Synonym: CAMKA
- Molecular Weight
- 80.3 kDa
- NCBI Accession
- NP_741960
- Pathways
- WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
-
