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CFHR5 Protein (His tag)

CFHR5 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318330
  • Target See all CFHR5 Proteins
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CFHR5 protein is labelled with His tag.
    Purpose
    Recombinant Human CFHR5 Protein (His Tag)
    Sequence
    Glu19-Glu569
    Characteristics
    Recombinant Human Complement Factor H-Related 5 is produced by our Mammalian expression system and the target gene encoding Glu19-Glu569 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product CFHR5 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    Alternative Name
    CFHR5 (CFHR5 Products)
    Synonyms
    CFHL5 Protein, CFHR5D Protein, FHR-5 Protein, FHR5 Protein, complement factor H related 5 Protein, CFHR5 Protein
    Background

    Background: Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.

    Synonym: Complement factor H-related protein 5,CFHR5,CFHL5,FHR5

    Molecular Weight
    63.5 kDa
    UniProt
    Q9BXR6
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