CFHR5 Protein (His tag)
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- Target See all CFHR5 Proteins
- CFHR5 (Complement Factor H-Related 5 (CFHR5))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CFHR5 protein is labelled with His tag.
- Purpose
- Recombinant Human CFHR5 Protein (His Tag)
- Sequence
- Glu19-Glu569
- Characteristics
- Recombinant Human Complement Factor H-Related 5 is produced by our Mammalian expression system and the target gene encoding Glu19-Glu569 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CFHR5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CFHR5 (Complement Factor H-Related 5 (CFHR5))
- Alternative Name
- CFHR5 (CFHR5 Products)
- Synonyms
- CFHL5 Protein, CFHR5D Protein, FHR-5 Protein, FHR5 Protein, complement factor H related 5 Protein, CFHR5 Protein
- Background
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Background: Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
Synonym: Complement factor H-related protein 5,CFHR5,CFHL5,FHR5
- Molecular Weight
- 63.5 kDa
- UniProt
- Q9BXR6
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