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CFHR5 Products

(Complement Factor H-Related 5 (CFHR5))

Categories

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010].

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Featured CFHR5 Categories

CFHR5 Antibodies

High quality antibodies with extensive validation data.

CFHR5 ELISA Kits

Reliable ELISA kits for a wide range of species.

CFHR5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CFHR5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC
Validations
  • (7)
Cat. No. ABIN5542639
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS, IHC, ICC
Validations
  • (8)
Cat. No. ABIN5542640
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN651876
Quantity 400 μL
Datasheet Datasheet

Recommended CFHR5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955035
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2702908
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6386029
Quantity 96 tests
Datasheet Datasheet

Recommended CFHR5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349213
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080024
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1880676
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CFHR5 products

Berra, Clivio: "Rapid isolation of pure Complement Factor H from serum for functional studies by the use of a monoclonal antibody that discriminates FH from all the other isoforms." in: Molecular immunology, Vol. 72, pp. 65-73, (2016) (PubMed).

Medjeral-Thomas, Malik, Patel, Toth, Cook, Tomson, Pickering: "A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry." in: Kidney international, Vol. 85, Issue 4, pp. 933-7, (2014) (PubMed).

Synonyms and alternative names related to CFHR5

complement factor H related 5 (CFHR5), CFHL5, CFHR5D, FHR-5, FHR5

Protein level used designations for CFHR5

  • complement factor H-related protein 5
  • factor H-related protein 5
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