DCUN1D1 Protein (His tag)
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- Target See all DCUN1D1 Proteins
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCUN1D1 protein is labelled with His tag.
- Purpose
- Recombinant Human DCUN1D1 Protein (His Tag)
- Sequence
- Met 1-Val259
- Characteristics
- Recombinant Human DCN1-Like Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Val259 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DCUN1D1 Protein
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Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (His tag)
custom-made DCUN1D1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (His tag)DCUN1D1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (GST tag)DCUN1D1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (His tag)custom-made DCUN1D1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259), (full length) protein (His-SUMO Tag)DCUN1D1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) protein (Myc-DYKDDDDK Tag)DCUN1D1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- Alternative Name
- DCUN1D1 (DCUN1D1 Products)
- Background
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Background: DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
Synonym: DCN1-Like Protein 1, DCUN1 Domain-Containing Protein 1, Defective in Cullin Neddylation Protein 1-Like Protein 1, Squamous Cell Carcinoma-Related Oncogene, DCUN1D1, DCUN1L1, RP42, SCCRO
- Molecular Weight
- 32.3 kDa
- UniProt
- Q96GG9
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