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IL20RB Protein (His tag)

IL20RB Origin: Rat Host: HEK-293 Cells Recombinant > 91 % as determined by SDS-PAGE
Catalog No. ABIN7321246
  • Target See all IL20RB Proteins
    IL20RB (Interleukin 20 Receptor beta (IL20RB))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    Rat
    Source
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL20RB protein is labelled with His tag.
    Purpose
    Recombinant Rat IL20RB Protein (His Tag)
    Sequence
    Met1-Pro227
    Characteristics
    A DNA sequence encoding the rat IL20RB (B8K1X9) (Met1-Pro227) was expressed, fused with a polyhistidine tag at the C-terminus.
    Purity
    > 91 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method
    Top Product
    Discover our top product IL20RB Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL20RB (Interleukin 20 Receptor beta (IL20RB))
    Alternative Name
    IL20RB (IL20RB Products)
    Background

    Background: IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons, cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.

    Synonym: IL20RB

    Molecular Weight
    24.6 kDa
    UniProt
    B8K1X9
    Pathways
    Regulation of Leukocyte Mediated Immunity
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