KYNU Protein (His tag)
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- Target See all KYNU Proteins
- KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This KYNU protein is labelled with His tag.
- Purpose
- Recombinant Mouse KYNU/Kynureninase Protein (His Tag)(Active)
- Sequence
- Met 1-Ser 464
- Characteristics
- A DNA sequence encoding the mouse KYNU (Q9CXF0) (Met 1-Ser 464) was expressed,with a C-terminal polyhistidine tag.
- Purity
- > 94 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to oxidize 3-hydroxykynurenine.The specific activity is > 100 pmoles/min/μg.
- Top Product
- Discover our top product KYNU Protein
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Kynureninase (L-Kynurenine Hydrolase) (KYNU) (AA 1-307) protein (GST tag)
KYNU Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Kynureninase (L-Kynurenine Hydrolase) (KYNU) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)KYNU Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))
- Alternative Name
- KYNU/Kynureninase (KYNU Products)
- Background
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Background: Genetic studies in mouse and human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population.The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension.
Synonym: 4432411A05Rik
- Molecular Weight
- 53.7 kDa
- UniProt
- Q9CXF0
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