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REG3D Protein (His tag)

REG3D Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Catalog No. ABIN7197673
  • Target
    REG3D (Regenerating Islet-Derived 3 delta (REG3D))
    Protein Type
    Recombinant
    Origin
    Mouse
    Source
    HEK-293 Cells
    Purification tag / Conjugate
    This REG3D protein is labelled with His tag.
    Purpose
    Recombinant Mouse REG3D Protein (His Tag)
    Sequence
    Met 1-Gly 175
    Characteristics
    A DNA sequence encoding the mouse REG3D isoform 1 (NP_038921.2) extracellular domain (Met 1-Gly 175) was fused with a polyhistidine tag at the C-terminus.
    Purity
    > 97 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    REG3D (Regenerating Islet-Derived 3 delta (REG3D))
    Alternative Name
    REG3D
    Synonyms
    INGAP Protein, Ingaprp Protein, regenerating islet-derived 3 delta Protein, Reg3d Protein
    Background

    Background: Regenerating islet-derived 3 delta (REG3D) is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated in pancreatic beta-cell regeneration. Reg proteins are expressed in various organs and are involved in cancers and neurodegenerative diseases. They display a typical C-type lectin-like domain but possess additional highly conserved amino acids.

    Synonym: INGAP,Ingaprp,MGC130575,Reg3d

    Molecular Weight
    18.5 kDa
    NCBI Accession
    NP_038921
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