Annexin a1 Protein (AA 1-346) (His tag)
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- Target See all Annexin a1 (ANXA1) Proteins
- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-346
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Annexin a1 protein is labelled with His tag.
- Purpose
- Human ANXA1 Protein
- Sequence
- Met1-Asn346
- Characteristics
- Recombinant Human ANXA1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Asn346.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ANXA1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
- Alternative Name
- ANXA1 (ANXA1 Products)
- Background
- Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance.
- Molecular Weight
- 39.5 kDa same as Tris-Bis PAGE result.
- UniProt
- P04083
- Pathways
- Hormone Transport
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