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SLC3A2 Protein (AA 206-630) (His tag)

SLC3A2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274265
  • Target See all SLC3A2 Proteins
    SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 206-630
    Origin
    • 14
    • 4
    • 4
    • 1
    • 1
    Human
    Source
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This SLC3A2 protein is labelled with His tag.
    Purpose
    Human CD98 Protein
    Sequence
    Arg206-Ala630
    Characteristics
    Recombinant Human CD98 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Arg206-Ala630.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
    Alternative Name
    CD98 (SLC3A2 Products)
    Synonyms
    4F2 Protein, 4F2HC Protein, 4T2HC Protein, CD98 Protein, CD98HC Protein, MDU1 Protein, NACAE Protein, Mdu1 Protein, MGC53951 Protein, slc3a2 Protein, MGC53965 Protein, SLC3A2 Protein, AI314110 Protein, Cd98 Protein, Ly-10 Protein, Ly-m10 Protein, Ly10 Protein, Mgp-2hc Protein, fc65h12 Protein, wu:fc65h12 Protein, id:ibd1327 Protein, sb:cb519 Protein, wu:fe14a07 Protein, wu:fq18d12 Protein, zgc:55813 Protein, solute carrier family 3 member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog Protein, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2a Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2b Protein, SLC3A2 Protein, Slc3a2 Protein, slc3a2.L Protein, slc3a2.S Protein, slc3a2a Protein, slc3a2b Protein
    Background
    The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.
    Molecular Weight
    47.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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