CADM3 Protein (AA 23-326) (His tag)

Catalog No. ABIN7274327

Product Details

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Protein Type: Recombinant

Protein Characteristics: AA 23-326

Origin: Cynomolgus

Source: HEK-293 Cells

Purification tag / Conjugate: This CADM3 protein is labelled with His tag.

Purpose: Cynomolgus CADM3 Protein

Sequence: Asn23-Thr326

Characteristics: Recombinant Cynomolgus CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn23-Thr326.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Alternative Name: CADM3 (CADM3 Products)

Synonyms: BIgR Protein, IGSF4B Protein, NECL1 Protein, Necl-1 Protein, TSLL1 Protein, synCAM3 Protein, Igsf4b Protein, Necl1 Protein, SynCAM3 Protein, Tsll1 Protein, necl1 Protein, cell adhesion molecule 3 Protein, cell adhesion molecule 3 S homeolog Protein, CADM3 Protein, Cadm3 Protein, cadm3.S Protein

Background: Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.

Molecular Weight: 34.46 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5UJL5

Pathways: Cell-Cell Junction Organization