AIMP1 Protein (AA 2-312) (His tag)

Catalog No. ABIN7274505

Product Details

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Protein Type: Recombinant

Protein Characteristics: AA 2-312

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This AIMP1 protein is labelled with His tag.

Purpose: Human EMAP-II/AIMP1 Protein

Sequence: Ala2-Lys312

Characteristics: Recombinant Human EMAP-II/AIMP1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ala2-Lys312.

Purity: > 95 % as determined by Tris-Bis PAGE

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human EMAP-II, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-EMAP-II Antibody, hFc Tag with the EC50 of 0.18ug/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 8.0).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Alternative Name: EMAP-II (AIMP1 Products)

Synonyms: EMAP2 Protein, EMAPII Protein, HLD3 Protein, SCYE1 Protein, p43 Protein, wu:fa95a05 Protein, zgc:154081 Protein, AIMP1 Protein, 9830137A06Rik Protein, AIMP1/p43 Protein, Emap2 Protein, Scye1 Protein, scye1 Protein, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog Protein, AIMP1 Protein, aimp1 Protein, Aimp1 Protein, aimp1.S Protein

Background: The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely related to the periods of vascularization and alveolarization in the developing lung. Hence the study of EMAP II could play a vital role in studying and devising appropriate therapeutics for diseases of aberrant lung development, such as BPD.

Molecular Weight: 35.4 kDa. The protein migrates to 40-45 kDa based on Tris-Bis PAGE result.