FCRL2 Protein (AA 20-401) (His tag)
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- Target See all FCRL2 Proteins
- FCRL2 (Fc Receptor-Like 2 (FCRL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-401
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FCRL2 protein is labelled with His tag.
- Purpose
- Human FCRL2/IRTA4 Protein
- Sequence
- Leu20-Val401
- Characteristics
- Recombinant Human FCRL2/IRTA4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Val401.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human FCRL2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA. See testing image for detail.
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Fc Receptor-Like 2 (FCRL2) (AA 20-401) protein (His tag)
Crystallography grade FCRL2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, Crys, WB
Fc Receptor-Like 2 (FCRL2) (AA 20-508) protein (rho-1D4 tag)Crystallography grade FCRL2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, Crys, WB
Fc Receptor-Like 2 (FCRL2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FCRL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FCRL2 (Fc Receptor-Like 2 (FCRL2))
- Alternative Name
- FCRL2 (FCRL2 Products)
- Synonyms
- CD307b Protein, FCRH2 Protein, IFGP4 Protein, IRTA4 Protein, SPAP1 Protein, SPAP1A Protein, SPAP1B Protein, SPAP1C Protein, fcrh2 Protein, ifgp4 Protein, irta4 Protein, spap1 Protein, spap1a Protein, spap1b Protein, spap1c Protein, Fc receptor like 2 Protein, Fc receptor-like 2 Protein, Fc receptor-like protein 2 Protein, Fc receptor-like 2 L homeolog Protein, FCRL2 Protein, LOC612038 Protein, fcrl2.L Protein
- Background
- Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation, P < 0.0001) and cells of other hematological diseases.
- Molecular Weight
- 42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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