FCRL2 Protein (AA 20-401) (His tag)
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- Target See all FCRL2 Proteins
- FCRL2 (Fc Receptor-Like 2 (FCRL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-401
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FCRL2 protein is labelled with His tag.
- Purpose
- Human FCRL2/IRTA4 Protein
- Sequence
- Leu20-Val401
- Characteristics
- Recombinant Human FCRL2/IRTA4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-Val401.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human FCRL2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA. See testing image for detail.
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Fc Receptor-Like 2 (FCRL2) (AA 20-398) protein (His tag)
FCRL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Fc Receptor-Like 2 (FCRL2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FCRL2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FCRL2 (Fc Receptor-Like 2 (FCRL2))
- Alternative Name
- FCRL2 (FCRL2 Products)
- Background
- Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation, P < 0.0001) and cells of other hematological diseases.
- Molecular Weight
- 42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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