MMP2 Protein (AA 34-660) (His tag)
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- Target See all MMP2 Proteins
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-660
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP2 protein is labelled with His tag.
- Purpose
- Human MMP-2 Protein (pro form)
- Sequence
- Ile34-Cys660
- Characteristics
- Recombinant Human MMP-2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile34-Cys660.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MMP2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 25 mM Tris, 150 mM NaCl, 50 % Glycerol ( pH 7.5).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Alternative Name
- MMP-2 (MMP2 Products)
- Background
- Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many cardiovascular pathologies (e.g., myocardial infarction, hypertensive heart disease) where tissue remodeling and inflammatory responses are perturbed.
- Molecular Weight
- 71.6 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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