VSIG4 Protein (AA 25-288) (His tag)
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- Target See all VSIG4 Proteins
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-288
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VSIG4 protein is labelled with His tag.
- Purpose
- Cynomolgus VSIG4 Protein
- Sequence
- Arg25-Ala288
- Characteristics
- Recombinant Cynomolgus VSIG4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg25-Ala288.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product VSIG4 Protein
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V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 20-283) protein (His tag)
VSIG4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) protein (His tag,Fc Tag)VSIG4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) protein (His tag)VSIG4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- Alternative Name
- VSIG4 (VSIG4 Products)
- Background
- VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
- Molecular Weight
- 30.16 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A7N9D9P6
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