BTK Protein (AA 1-659) (DYKDDDDK Tag)
-
- Target See all BTK Proteins
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-659
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BTK protein is labelled with DYKDDDDK Tag.
- Purpose
- Recombinant Human BTK Protein with C-terminal 3xFlag tag
- Specificity
- BTK (Met1-Ser659) 3xFlag tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
-
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 1-659) protein (GST tag)
BTK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 100-189) protein (GST tag)BTK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 2-659) protein (His tag)BTK Origin: Human Host: Yeast Recombinant > 90 % SDS
Bruton Agammaglobulinemia tyrosine Kinase (BTK) protein (Myc-DYKDDDDK Tag)BTK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Alternative Name
- BTK (BTK Products)
- Background
- The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
- Molecular Weight
- predicted molecular mass of 79.2 kDa after removal of the signal peptide.
- UniProt
- Q06187
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
-
