CCL19 Protein (AA 22-98) (Fc Tag)
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- Target See all CCL19 Proteins
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-98
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCL19 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CCL19 Protein with C-terminal human Fc tag
- Specificity
- CCL19 (Gly22-Ser98) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CCL19 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Alternative Name
- CCL19 (CCL19 Products)
- Background
- This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]
- Molecular Weight
- predicted molecular mass of 34.9 kDa after removal of the signal peptide. The apparent molecular mass of CCL19-hFc is 25-55 kDa due to glycosylation.
- UniProt
- Q99731
- Pathways
- Positive Regulation of Immune Effector Process
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