tau-441 (Lys18), (Pro301Leu-Mutant) Protein
HPLC verified
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
95 %
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- Target
- tau-441
- Protein Type
- Recombinant
- Protein Characteristics
- Lys18, Pro301Leu-Mutant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)
- Sequence
- Gln 244 - Glu 372
- Characteristics
- Human Tau-441 (K18, P301L) Protein, Tag Free is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L).
- Purity
- 95 %
- Endotoxin Level
- 0.1 EU per μg
- Grade
- HPLC verified
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tau-441 (AA 1-441) protein (His tag)
Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reduced SDS-PAGE.
-
- Comment
-
This protein carries no "tag". () The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5
- Storage
- -80 °C
- Storage Comment
- -70°C
-
- Target
- tau-441
- Alternative Name
- Tau-441
- Background
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
- Molecular Weight
- 13.8 kDa
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