tau-441 (Pro301Leu-Mutant) protein (His tag)
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
90 %
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- Target
- tau-441
- Protein Type
- Recombinant
- Protein Characteristics
- Pro301Leu-Mutant
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- His tag
- Purpose
- Human Tau-441 / 2N4R (P301L) Protein, His Tag
- Sequence
- Met 1 - Leu 441
- Characteristics
- Human Tau-441 (P301L), His Tag is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 (P301L).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
-
tau-441 (AA 1-441) protein (His tag)
Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reduced SDS-PAGE.
-
- Comment
-
This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 47.8 kDa. The protein migrates as 38-66 kDa under reducing (R) condition (SDS-PAGE).
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
-
- Target
- tau-441
- Background
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
- Molecular Weight
- 47.8 kDa
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