Nerve Growth Factor Protein (NGF) (AA 122-241) (His tag)
-
- Target See all Nerve Growth Factor (NGF) Proteins
- Nerve Growth Factor (NGF)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 122-241
-
Origin
- Mouse
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Nerve Growth Factor protein is labelled with His tag.
- Sequence
- Ser 122-Gly 241
- Characteristics
- A DNA sequence encoding the Mouse NGF/NGFB/beta-NGF protein (P01139) (Ser 122-Gly 241) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product NGF Protein
-
Nerve Growth Factor (NGF) (AA 122-239) protein (His tag)
NGF Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nerve Growth Factor (NGF) (AA 200-299) protein (GST tag)NGF Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- Nerve Growth Factor (NGF)
- Alternative Name
- NGF (NGF Products)
- Background
-
Abbreviation: NGF,NGFB,beta-NGF
Target Synonym: Beta-Nerve Growth Factor,Beta-NGF,NGF,NGFB
Background: NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90 % homology at the amino acid level with human beta -NGF and 95.8 % with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
- Molecular Weight
-
Calculated MW: 13.09 kDa
Observed MW: 15 kDa
- UniProt
- P01139
- Pathways
- Regulation of Cell Size
-
