CD63 Protein (CD63) (AA 103-203) (His tag)

Catalog No. ABIN7505672

Product Details

Target: CD63

Protein Type: Recombinant

Protein Characteristics: AA 103-203

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD63 protein is labelled with His tag.

Sequence: Ala 103-Val 203

Characteristics: A DNA sequence encoding the Human CD63 protein (P08962) (103-203) was expressed with a C-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CD63

Alternative Name: CD63 (CD63 Products)

Background:

Abbreviation: CD63

Target Synonym: CD63 antigen,Granulophysin,Lysosomal-associated membrane protein 3,LAMP-3,Melanoma-associated antigen ME491,OMA81H,Ocular melanoma-associated antigen,Tetraspanin-30,Tspan-30,CD antigen CD63

Background: There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 63 (CD63) is a member of the CD family and the transmembrane 4 superfamily,also known as the tetraspanin family. CD63 is a cellular surface glycoprotein characterized by the presence of four bydrophobic domains. CD63 had functions in mediating signal transduction processes and then regulate variety of cellular processes such as cell proliferation, activation and motility. It has reported that CD63 protein associated with tumor progression and served as a blood platlet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome.

Molecular Weight:

Calculated MW: 11 kDa

Observed MW: 20 kDa

UniProt: P08962