C4B Protein (AA 20-673) (His tag)

Catalog No. ABIN7505776

Product Details

Target: C4B (C4b) (Complement Component C4b (C4b))

Protein Type: Recombinant

Protein Characteristics: AA 20-673

Origin: Rat

Source: HEK-293 Cells

Purification tag / Conjugate: This C4B protein is labelled with His tag.

Sequence: Lys20-Ser673

Characteristics: A DNA sequence encoding the Rat C4 protein (P08649) (Lys20-Ser673) was expressed with a C-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: C4B (C4b) (Complement Component C4b (C4b))

Alternative Name: Complement C4b (C4b Products)

Background:

Abbreviation: Complement C4b,C4b

Target Synonym: Complement C4 beta chain,Complement C4,C4,C4b,CO4

Background: Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes.

Molecular Weight:

Calculated MW: 71.83 kDa

Observed MW: 70 kDa

UniProt: P08649

Pathways: Complement System