TMEM170B Protein (AA 1-132) (His tag)
custom-made
TMEM170B
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all TMEM170B products
- TMEM170B (Transmembrane Protein 170B (TMEM170B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-132
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM170B protein is labelled with His tag.
- Purpose
- Made-to-order recombinant TMEM170B Protein expressed in mammalian cells.
- Sequence
- MKAEGGDHSM INLSVQQVLS LWAHGTVLRN LTEMWYWIFL WALFSSLFVH GAAGVLMFVM LQRHRQGRVI SVIAVSIGFL ASVTGAMITS AAVAGIYRVA GKNMAPLEAL VWGVGQTVLT LIISFSRILA TL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 170B (TMEM170B) (AA 1-132) protein (His tag)
custom-made TMEM170B Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TMEM170B (Transmembrane Protein 170B (TMEM170B))
- Alternative Name
- TMEM170B (TMEM170B Products)
- Background
- Transmembrane protein 170B,FUNCTION: Negatively regulates the canonical Wnt signaling in breast cancer cells. Exerts an inhibitory effect on breast cancer growth by inhibiting CTNNB1 stabilization and nucleus translocation, which reduces the activity of Wnt targets (PubMed:29367600). {ECO:0000269|PubMed:29367600}.
- Molecular Weight
- 14.4 kDa
- UniProt
- Q5T4T1
- AlphaFold
- Q5T4T1
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