TMEM39A Protein (AA 1-488) (His tag)
custom-made
TMEM39A
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all TMEM39A products
- TMEM39A (Transmembrane Protein 39A (TMEM39A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-488
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM39A protein is labelled with His tag.
- Purpose
- Custom-made recombinant TMEM39A Protein expressed in mammalian cells.
- Sequence
- MPGGRRGPSR QQLSRSALPS LQTLVGGGCG NGTGLRNRNG SAIGLPVPPI TALITPGPVR HCQIPDLPVD GSLLFEFLFF IYLLVALFIQ YINIYKTVWW YPYNHPASCT SLNFHLIDYH LAAFITVMLA RRLVWALISE ATKAGAASMI HYMVLISARL VLLTLCGWVL CWTLVNLFRS HSVLNLLFLG YPFGVYVPLC CFHQDSRAHL LLTDYNYVVQ HEAVEESAST VGGLAKSKDF LSLLLESLKE QFNNATPIPT HSCPLSPDLI RNEVECLKAD FNHRIKEVLF NSLFSAYYVA FLPLCFVKST QYYDMRWSCE HLIMVWINAF VMLTTQLLPS KYCDLLHKSA AHLGKWQKLE HGSYSNAPQH IWSENTIWPQ GVLVRHSRCL YRAMGPYNVA VPSDVSHARF YFLFHRPLRL LNLLILIEGS VVFYQLYSLL RSEKWNHTLS MALILFCNYY VLFKLLRDRI VLGRAYSYPL NSYELKAN Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 39A (TMEM39A) (AA 1-488) protein (GST tag)
TMEM39A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TMEM39A (Transmembrane Protein 39A (TMEM39A))
- Alternative Name
- TMEM39A (TMEM39A Products)
- Background
- Transmembrane protein 39A,FUNCTION: Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools (PubMed:31806350). Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L (PubMed:31806350). {ECO:0000269|PubMed:31806350}., FUNCTION: (Microbial infection) Positively regulates the replication of encephalomyocarditis virus (EMCV) via autophagy-dependent pathway. {ECO:0000269|PubMed:31849860}.
- Molecular Weight
- 55.7 kDa
- UniProt
- Q9NV64
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