ELOVL3 Protein (AA 1-270) (His tag)
custom-made
ELOVL3
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all ELOVL3 products
- ELOVL3 (ELOVL Fatty Acid Elongase 3 (ELOVL3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-270
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ELOVL3 protein is labelled with His tag.
- Purpose
- Custom-made recombinant ELOVL3 Protein expressed in mammalian cells.
- Sequence
- MVTAMNVSHE VNQLFQPYNF ELSKDMRPFF EEYWATSFPI ALIYLVLIAV GQNYMKERKG FNLQGPLILW SFCLAIFSIL GAVRMWGIMG TVLLTGGLKQ TVCFINFIDN STVKFWSWVF LLSKVIELGD TAFIILRKRP LIFIHWYHHS TVLVYTSFGY KNKVPAGGWF VTMNFGVHAI MYTYYTLKAA NVKPPKMLPM LITSLQILQM FVGAIVSILT YIWRQDQGCH TTMEHLFWSF ILYMTYFILF AHFFCQTYIR PKVKAKTKSQ Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- ELOVL3 (ELOVL Fatty Acid Elongase 3 (ELOVL3))
- Alternative Name
- ELOVL3 (ELOVL3 Products)
- Background
- Very long chain fatty acid elongase 3 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL3) (Cold-inducible glycoprotein of 30 kDa) (ELOVL fatty acid elongase 3) (ELOVL FA elongase 3) (Elongation of very long chain fatty acids protein 3) (Very long chain 3-ketoacyl-CoA synthase 3) (Very long chain 3-oxoacyl-CoA synthase 3),FUNCTION: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000255|HAMAP-Rule:MF_03203, ECO:0000269|PubMed:20937905}.
- Molecular Weight
- 31.5 kDa
- UniProt
- Q9HB03
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