GCM1 Protein (AA 1-436) (His tag)
custom-made
GCM1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all GCM1 Proteins
- GCM1 (Glial Cells Missing Homolog 1 (GCM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-436
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GCM1 protein is labelled with His tag.
- Purpose
- Custom-made recombinant GCM1 Protein expressed in mammalian cells.
- Sequence
- MEPDDFDSED KEILSWDIND VKLPQNVKKT DWFQEWPDSY AKHIYSSEDK NAQRHLSSWA MRNTNNHNSR ILKKSCLGVV VCGRDCLAEE GRKIYLRPAI CDKARQKQQR KRCPNCDGPL KLIPCRGHGG FPVTNFWRHD GRFIFFQSKG EHDHPKPETK LEAEARRAMK KVNTAPSSVS LSLKGSTETR SLPGETQSQG SLPLTWSFQE GVQLPGSYSG HLIANTPQQN SLNDCFSFSK SYGLGGITDL TDQTSTVDPM KLYEKRKLSS SRTYSSGDLL PPSASGVYSD HGDLQAWSKN AALGRNHLAD NCYSNYPFPL TSWPCSFSPS QNSSEPFYQQ LPLEPPAAKT GCPPLWPNPA GNLYEEKVHV DFNSYVQSPA YHSPQEDPFL FTYASHPHQQ YSLPSKSSKW DFEEEMTYLG LDHCNNDMLL NLCPLR Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product GCM1 Protein
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Glial Cells Missing Homolog 1 (GCM1) protein (His tag)
GCM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- GCM1 (Glial Cells Missing Homolog 1 (GCM1))
- Alternative Name
- GCM1 (GCM1 Products)
- Background
- Chorion-specific transcription factor GCMa (hGCMa) (GCM motif protein 1) (Glial cells missing homolog 1),FUNCTION: Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes (PubMed:10542267, PubMed:18160678). Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer (PubMed:10542267). Binds to the SYDE1 promoter (PubMed:27917469). Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (PubMed:19219068). {ECO:0000269|PubMed:10542267, ECO:0000269|PubMed:18160678, ECO:0000269|PubMed:19219068, ECO:0000269|PubMed:27917469}.
- Molecular Weight
- 49.3 kDa
- UniProt
- Q9NP62
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