Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (AA 1-342) protein (His tag)
custom-made
HS3ST6
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) Proteins
- Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-342
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Custom-made recombinant HS3ST6 Protein expressed in mammalian cells.
- Sequence
- MAGSGGLGGG AGGGQGAGAG QGAALRASRA PMLLVALVLG AYCLCALPGR CPPAARAPAP APAPSEPSSS VHRPGAPGLP LASGPGRRRF PQALIVGVKK GGTRALLEFL RLHPDVRALG SEPHFFDRCY ERGLAWYRSL MPRTLDGQIT MEKTPSYFVT REAPRRIHAM SPDTKLIVVV RNPVTRAISD YAQTLSKTPG LPSFRALAFR HGLGPVDTAW SAVRIGLYAQ HLDHWLRYFP LSHFLFVSGE RLVSDPAGEV GRVQDFLGLK RVVTDKHFYF NATKGFPCLK KAQGGSRPRC LGKSKGRPHP RVPQALVRRL QEFYRPFNRR FYQMTGQDFG WG Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6) (AA 1-342) protein (His tag)
custom-made HS3ST6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 6 (HS3ST6)
- Alternative Name
- HS3ST6 (HS3ST6 Products)
- Background
- Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (3-OST-6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6),FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. {ECO:0000269|PubMed:15303968}.
- Molecular Weight
- 37.2 kDa
- UniProt
- Q96QI5
- AlphaFold
- Q96QI5
- Pathways
- Glycosaminoglycan Metabolic Process
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