POLR2L Protein (AA 1-67) (Fc Tag)
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- Target See all POLR2L Proteins
- POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-67
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This POLR2L protein is labelled with Fc Tag.
- Purpose
- Custom-made recombinant POLR2L Protein expressed in mammalian cells.
- Sequence
- MIIPVRCFTC GKIVGNKWEA YLGLLQAEYT EGDALDALGL KRYCCRRMLL AHVDLIEKLL NYAPLEK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product POLR2L Protein
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Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L) (AA 1-67) protein (Fc Tag)
custom-made POLR2L Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L) (AA 1-67) protein (GST tag)POLR2L Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L) protein (Myc-DYKDDDDK Tag)POLR2L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))
- Alternative Name
- POLR2L (POLR2L Products)
- Background
- DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog),FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. {ECO:0000250, ECO:0000250|UniProtKB:P22139, ECO:0000269|PubMed:16809778, ECO:0000269|PubMed:20413673, ECO:0000269|PubMed:27193682, ECO:0000269|PubMed:30190596, ECO:0000269|PubMed:34671025, ECO:0000269|PubMed:34887565, ECO:0000269|PubMed:36271492, ECO:0000269|PubMed:9852112}.
- Molecular Weight
- 7.6 kDa
- UniProt
- P62875
- AlphaFold
- P62875
- Pathways
- Regulatory RNA Pathways
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