UNK Protein (AA 1-810) (His tag)
custom-made
UNK
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all UNK products
- UNK (Unkempt Homolog (Drosophila) (UNK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-810
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UNK protein is labelled with His tag.
- Purpose
- Custom-made recombinant UNK Protein expressed in mammalian cells.
- Sequence
- MSKGPGPGGS AASSAPPAAT AQVLQAQPEK PQHYTYLKEF RTEQCPLFVQ HKCTQHRPYT CFHWHFVNQR RRRSIRRRDG TFNYSPDVYC TKYDEATGLC PEGDECPFLH RTTGDTERRY HLRYYKTGIC IHETDSKGNC TKNGLHCAFA HGPHDLRSPV YDIRELQAME ALQNGQTTVE GSIEGQSAGA ASHAMIEKIL SEEPRWQETA YVLGNYKTEP CKKPPRLCRQ GYACPYYHNS KDRRRSPRKH KYRSSPCPNV KHGDEWGDPG KCENGDACQY CHTRTEQQFH PEIYKSTKCN DMQQSGSCPR GPFCAFAHVE QPPLSDDLQP SSAVSSPTQP GPVLYMPSAA GDSVPVSPSS PHAPDLSALL CRNSSLGSPS NLCGSPPGSI RKPPNLEGIV FPGESGLAPG SYKKAPGFER EDQVGAEYLK NFKCQAKLKP HSLEPRSQEQ PLLQPKQDML GILPAGSPLT SSISSSITSS LAATPPSPVG TSSVPGMNAN ALPFYPTSDT VESVIESALD DLDLNEFGVA ALEKTFDNST VPHPGSITIG GSLLQSSAPV NIPGSLGSSA SFHSASPSPP VSLSSHFLQQ PQGHLSQSEN TFLGTSASHG SLGLNGMNSS IWEHFASGSF SPGTSPAFLS GPGAAELARL RQELDEANST IKQWEESWKQ AKQACDAWKK EAEEAGERAS AAGAECELAR EQRDALEVQV KKLQEELERL HAGPEPQALP AFSDLEALSL STLYSLQKQL RAHLEQVDKA VFHMQSVKCL KCQEQKRAVL PCQHAALCEL CAEGSECPIC QPGRAHTLQS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- UNK (Unkempt Homolog (Drosophila) (UNK))
- Alternative Name
- UNK (UNK Products)
- Background
- RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5),FUNCTION: Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280). {ECO:0000269|PubMed:25737280}.
- Molecular Weight
- 88.1 kDa
- UniProt
- Q9C0B0
- AlphaFold
- Q9C0B0
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