URGCP Protein (AA 1-931) (His tag)

Catalog No. ABIN7555979

Product Details

Target: URGCP (Upregulator of Cell Proliferation (URGCP))

Protein Type: Recombinant

Protein Characteristics: AA 1-931

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This URGCP protein is labelled with His tag.

Purpose: Custom-made recombinant URGCP Protein expressed in mammalian cells.

Sequence: MASPGIEVEL LGKGHSDLGE VAPEIKASER RTAVAIADLE WREMEGDDCE FRYGDGTNEA QDNDFPTVER SRLQEMLSLL GLETYQVQKL SLQDSLQISF DSMKNWAPQV PKDLPWNFLR KLQALNADAR NTTMVLDVLP DARPVEKESQ MEEEIIYWDP ADDLAADIYS FSELPTPDTP VNPLDLLCAL LLSSDSFLQQ EIALKMALCQ FALPLVLPDS ENHYHTFLLW AMRGIVRTWW SQPPRGMGSF REDSVVLSRA PAFAFVRMDV SSNSKSQLLN AVLSPGHRQW DCFWHRDLNL GTNAREISDG LVEISWFFPS GREDLDIFPE PVAFLNLRGD IGSHWLQFKL LTEISSAVFI LTDNISKKEY KLLYSMKEST TKYYFILSPY RGKRNTNLRF LNKLIPVLKI DHSHVLVKVS STDSDSFVKR IRAIVGNVLR APCRRVSVED MAHAARKLGL KVDEDCEECQ KAKDRMERIT RKIKDSDAYR RDELRLQGDP WRKAAQVEKE FCQLQWAVDP PEKHRAELRR RLLELRMQQN GHDPSSGVQE FISGISSPSL SEKQYFLRWM EWGLARVAQP RLRQPPETLL TLRPKHGGTT DVGEPLWPEP LGVEHFLREM GQFYEAESCL VEAGRLPAGQ RRFAHFPGLA SELLLTGLPL ELIDGSTLSM PVRWVTGLLK ELHVRLERRS RLVVLSTVGV PGTGKSTLLN TMFGLRFATG KSCGPRGAFM QLITVAEGFS QDLGCDHILV IDSGGLIGGA LTSAGDRFEL EASLATLLMG LSNVTVISLA ETKDIPAAIL HAFLRLEKTG HMPNYQFVYQ NLHDVSVPGP RPRDKRQLLD PPGDLSRAAA QMEKQGDGFR ALAGLAFCDP EKQHIWHIPG LWHGAPPMAA VSLAYSEAIF ELKRCLLENI RNGLSNQNKN IQQLIELVRR L Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: URGCP (Upregulator of Cell Proliferation (URGCP))

Alternative Name: URGCP (URGCP Products)

Background: Up-regulator of cell proliferation (HBV X protein up-regulated gene 4 protein) (HBxAg up-regulated gene 4 protein),FUNCTION: May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer. {ECO:0000269|PubMed:12082552, ECO:0000269|PubMed:17217616}.

Molecular Weight: 105.0 kDa

UniProt: Q8TCY9