TPM2 Protein (AA 1-284) (His tag)
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- Target See all TPM2 Proteins
- TPM2 (Tropomyosin-2 (TPM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-284
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TPM2 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Tpm2 Protein expressed in mammalian cells.
- Sequence
- MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKDAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAMKDEEK MELQEMQLKE AKHIAEDSDR KYEEVARKLV ILEGELERSE ERAEVAESKC GDLEEELKIV TNNLKSLEAQ ADKYSTKEDK YEEEIKLLEE KLKEAETRAE FAERSVAKLE KTIDDLEDEV YAQKMKYKAI SEELDNALND ITSL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product TPM2 Protein
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Tropomyosin-2 (TPM2) (AA 1-284) protein (His tag)
custom-made TPM2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tropomyosin-2 (TPM2) (AA 1-284) protein (GST tag)TPM2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Tropomyosin-2 (TPM2) (AA 14-284), (partial) protein (His tag)TPM2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Tropomyosin-2 (TPM2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TPM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tropomyosin-2 (TPM2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TPM2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TPM2 (Tropomyosin-2 (TPM2))
- Alternative Name
- Tpm2 (TPM2 Products)
- Background
- Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2),FUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (PubMed:16094730). {ECO:0000250|UniProtKB:P58775, ECO:0000269|PubMed:16094730}.
- Molecular Weight
- 32.8 kDa
- UniProt
- P58774
- AlphaFold
- P58774
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