GEMC1 Protein (AA 1-333) (His tag)
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- Target See all GEMC1 (GMNC) Proteins
- GEMC1 (GMNC) (Geminin Coiled-Coil Domain Containing (GMNC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-333
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GEMC1 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Gmnc Protein expressed in mammalian cells.
- Sequence
- MNSILPCQDQ YFVGGQSYNC PYSTTTSESG VDVSKETWVS FWAAGLLDNT ELQQAPQVLE SPSELSFPVL DSCSWEEAQL SSQLYRNKQL QDTLLQKEEE LARLHEENNH LRQYLNSTLV KRLEEKAKKL LSSDEFSKVF GKLRKEKRKP KEHRHSPAEI PQFKTAKRNL STEFSNCEEQ PGPHVDPWVL QTLGLKDLNT IDDTLPANYS ATTSHPRAVP SISSLFVHDA NGYANVPRDL HLDYVGQGTH GSHTTSIHQE DCHSFPRLSN PPVRVQTLPY HTADVSPNKT EMAFSTSLSP HCNVKTHSFH QGQAFVRRDE EGGWKFTWVP KQT Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product GMNC Protein
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- GEMC1 (GMNC) (Geminin Coiled-Coil Domain Containing (GMNC))
- Alternative Name
- Gmnc (GMNC Products)
- Background
- Geminin coiled-coil domain-containing protein 1,FUNCTION: Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity). {ECO:0000250}.
- Molecular Weight
- 37.8 kDa
- UniProt
- Q3URY2
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