MACROD2 Protein (AA 1-475) (His tag)
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- Target See all MACROD2 Proteins
- MACROD2 (MACRO Domain Containing 2 (MACROD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-475
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MACROD2 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Macrod2 Protein expressed in mammalian cells.
- Sequence
- MYPSNKKKKV WREEKERLLK MTLEERRKEY IRDYVSLSTI LSWKEEMKSK GQNDEENTQE APQMKKSLSE KVSLYRGDIT LLEVDAIVNA ANASLLGGGG VDGCIHRAAG PCLLAECRNL NGCETGHAKI TCGYDLPAKY VIHTVGPIAR GHINGSHKED LANCYQSSLK LVKENNLRSV AFPCISTGIY GFPNEPAAVI ALGTIKEWLA KNHQEVDRII FCVFLEVDFK IYKKKMNEFF PVDDNNEGTD ADMKEDSEGP EPKGLSPPHK KSKAKKPESS KDSSEDESGP EEKQTAEEME GQSQEAGGLR FLLRNLLGLI HRDGVNTTPV PSPASEDKAE VHKDEDSAKD DNTVKDSDMT NHSVCDQELP NGQENDSAKS EGKTEAESPS SSMETEDLSP NQEDAAIVEQ PEVIPLIDDQ EAQEGGEAQG KDAPAVFAES QGSSEAENTS GPDVDMNSQV DGVNEPTESL QEDLQ Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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MACRO Domain Containing 2 (MACROD2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)
MACROD2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
MACRO Domain Containing 2 (MACROD2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MACROD2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- MACROD2 (MACRO Domain Containing 2 (MACROD2))
- Alternative Name
- Macrod2 (MACROD2 Products)
- Background
- ADP-ribose glycohydrolase MACROD2 (MACRO domain-containing protein 2) (O-acetyl-ADP-ribose deacetylase MACROD2) (EC 3.5.1.-) ([Protein ADP-ribosylaspartate] hydrolase MACROD2) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD2) (EC 3.2.2.-),FUNCTION: Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. {ECO:0000250|UniProtKB:A1Z1Q3}.
- Molecular Weight
- 52.1 kDa
- UniProt
- Q3UYG8
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