Multicilin Protein (AA 1-379) (His tag)
custom-made
MCIDAS
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all Multicilin (MCIDAS) Proteins
- Multicilin (MCIDAS) (Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein (MCIDAS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-379
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Multicilin protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Mcidas Protein expressed in mammalian cells.
- Sequence
- MQACEGSAAG RRAFDSICPN RMLDLSRRTL GKPGKPERKF VPSWKSFSGC GGGSPVAVYE DPPDAEPAPL PALTTIDLQD LADCTSLLGT EASPSGDSSA SQNPSLQTEE DFNLQNFRDA MDDLIADSSS LMSPPLTNSD FPFSPCDVSS FGSCLSPSLD PPALGSPDLP PPPTEQYWKE VADQNQRALG TALIENNQLH VTLTQKQEEI ASLRERNVQL KELASRTRHL ASVLDKLMIT QSPAEPFQIK ATTKRSLEEL FCAAGQAGQG CAEVDAILRD ISQRCEEALH NRDPKRPRLQ PEPDSKDCSS RNLHGAFRGL RTDCSASSVN LSHSELEEGG SFSTPIRSHS TIRTLAFPQG KAFTIRTVTG GYKFRWVPS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product MCIDAS Protein
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Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein (MCIDAS) (AA 1-385) protein (His tag)
custom-made MCIDAS Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Multicilin (MCIDAS) (Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein (MCIDAS))
- Alternative Name
- Mcidas (MCIDAS Products)
- Background
- Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas),FUNCTION: Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. {ECO:0000250|UniProtKB:D6RGH6, ECO:0000250|UniProtKB:Q08B36}.
- Molecular Weight
- 41.1 kDa
- UniProt
- Q3UZ45
- AlphaFold
- Q3UZ45
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