FUT10 Protein (AA 1-481) (His tag)

Catalog No. ABIN7557448

Product Details

Target: FUT10 (Fucosyltransferase 10 (Alpha (1,3) Fucosyltransferase) (FUT10))

Protein Type: Recombinant

Protein Characteristics: AA 1-481

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This FUT10 protein is labelled with His tag.

Purpose: Made-to-order recombinant Fut10 Protein expressed in mammalian cells.

Sequence: MVRFQRRKLL ASCLCVTATV FLMVTLQVVV ELGKFERKKL KDSNVQDGHR DVEGEPKHLE PFPEKEALAL AGRTKVDAGS YPIVLWWSPL TGETGRLGQC GADACFFTIN RTFQHHPMTR AFLFYGTDFN IDSLPLPREA HHDWALFHEE SPKNNYKLFH KPVITLFNHT ATFSRHSHLP LTTQYLEGVD VLKSLRYLVP LQAKNNLRQK LAPLVYVQSD CDPPSDRDSY VRELMAYIEV DSYGECLQNR DLPQQLKNPA SMDADAFYRV IAQYKFILAF ENAVCDDYIT EKFWRPLKLG VVPVYYGSPT IADWLPSNRS AILVSEFSHP RELASFIRRL DYDDGLYETY VEWKLKGKIS NQRLLTALNE REWGVQDINQ DNYIDSFECM VCRRVWANSR LQEQGLPPKQ WKADVSHLHC PEPALFTFSS PASPALRGRS LRELWLPSFQ QSKKEAQALR WLVDRNQNFS SEEFWALVFK D Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: FUT10 (Fucosyltransferase 10 (Alpha (1,3) Fucosyltransferase) (FUT10))

Alternative Name: Fut10 (FUT10 Products)

Background: Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10),FUNCTION: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation (By similarity). Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (PubMed:23986452). {ECO:0000250|UniProtKB:Q6P4F1, ECO:0000269|PubMed:23986452}.

Molecular Weight: 55.7 kDa

UniProt: Q5F2L2

AlphaFold: Q5F2L2