FAM46C Protein (AA 1-391) (His tag)
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- Target See all FAM46C Proteins
- FAM46C (Family with Sequence Similarity 46, Member C (FAM46C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-391
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAM46C protein is labelled with His tag.
- Purpose
- Custom-made recombinant Tent5c Protein expressed in mammalian cells.
- Sequence
- MAEEGSSTKD SESFSVLNWD QVSRLHEVLT EVVPIHGRGN FPTLEITLKD IVQTVRGRLE EAGINVQDVR LNGSAAGHVL VKDNGLGCKD LDLIFHVALP TEAEFQLVRD VVLCSLLNFL PEGVNKLKIS PVTLKEAYVQ KLVKVCTDTD RWSLISLSNK NGRNVELKFV DSIRRQFEFS VDSFQIILDS LLFFYDCSGN PISEHFHPTV IGESMYGDFE EAFDHLQNRL IATKNPEEIR GGGLLKYSNL LVRDFRPADQ EEIKTLERYM CSRFFIDFPD ILEQQRKLET YLQNHFSDEE RSKYDYLMIL RRVVNESTVC LMGHERRQTL NLISLLALRV LAEQNIIPSA TNVTCYYQPA PYVSDGNFNN YYIAHPPITY SQPYPTWLPC N Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product FAM46C Protein
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Family with Sequence Similarity 46, Member C (FAM46C) (AA 1-391) protein (GST tag)
FAM46C Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Family with Sequence Similarity 46, Member C (FAM46C) (AA 1-391) protein (His tag)custom-made FAM46C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Family with Sequence Similarity 46, Member C (FAM46C) protein (Myc-DYKDDDDK Tag)FAM46C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- FAM46C (Family with Sequence Similarity 46, Member C (FAM46C))
- Alternative Name
- Tent5c (FAM46C Products)
- Background
- Terminal nucleotidyltransferase 5C (EC 2.7.7.19),FUNCTION: Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression (PubMed:34048638). Can also elongate RNA oligos ending with uridine molecule, provided that the sequence is adenosine-rich (By similarity). Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein (PubMed:28931820). {ECO:0000250|UniProtKB:Q5VWP2, ECO:0000269|PubMed:28931820, ECO:0000269|PubMed:34048638}.
- Molecular Weight
- 44.8 kDa
- UniProt
- Q5SSF7
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