BLOC1S3 Protein (AA 1-195) (His tag)
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- Target See all BLOC1S3 Proteins
- BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-195
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BLOC1S3 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Bloc1s3 Protein expressed in mammalian cells.
- Sequence
- MESSQGRRRR PGTVVPGEAA ETDSELSASS SEEELYLGPS GPTRGRPTGL RVAGEAAETD SEPEPEPTVV PVDLPPLVVQ RDPAETWGTE ETPAMAPARS LLQLRLAESQ TRLDHDVAAA VSGVYRRAGR DVAALAGRLA AAQATGLAAA HSVRLARGDL CALAERLDIV AGCRLLPDIR GVPGMEPEQD PGPRA Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product BLOC1S3 Protein
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Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3) (AA 1-202) protein (His tag)
custom-made BLOC1S3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3) protein (Myc-DYKDDDDK Tag)BLOC1S3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
- Alternative Name
- Bloc1s3 (BLOC1S3 Products)
- Background
- Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC-1 subunit 3) (Reduced pigmentation protein),FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:16760431, ECO:0000269|PubMed:19546860, ECO:0000269|PubMed:21998198}.
- Molecular Weight
- 20.4 kDa
- UniProt
- Q5U5M8
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