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MON1A Protein (AA 1-556) (His tag)

custom-made MON1A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7558047
  • Target See all MON1A Proteins
    MON1A (MON1 Homolog A (MON1A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-556
    Origin
    • 2
    • 1
    Mouse
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MON1A protein is labelled with His tag.
    Purpose
    Custom-made recombinant Mon1a Protein expressed in mammalian cells.
    Sequence
    MAADMQRKRS SECPEGTLAP SNGQSVERAE SPTPGLTQGT EPGAGQEGAM FVHTRSYEDL TELEDREASG DSPKECVGSP PPLATDMRQI SQDFSELSTQ LTGVARDLQE EMLPGSSEDW PEPQGAAGRG AATEPSQEGS TEGEEEDATE AWRLHQKHVF VLSEAGKPVY SRYGSEEALS STMGVMVALV SFLEADKNAI RSIHADGYKV VFVRRSPLVL VAVARTRQSA QELAQELLYI YYQILSLLTG AQLSHIFQQK QNYDLRRLLS GSERITDNLL QLMARDPSFL MGAARCLPLA AAVRDTVSAS LQQARARSLV FSILLAHNQL VALVRRKDQF LHPIDLHLLF NLISSSSSFR EGEAWTPVCL PKFNAAGFFH AHISYLEPDT DLCLLLISTD REDFFAVSDC RRRFQERLRK RGTHLALREA LRTPYYSVAQ VGIPDLRHFL YKSKSSGLFT SPEIEAPYSS EEEQERLLGL YQYLHSRAHN ASRPLKTIYY TGPNENLLAW VTGAFELYMC YSPLGTKASA VSAIHKLMRW IRKEEDRLFI LTPLTY Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    Specificity
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    Characteristics
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    Purity
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    Grade
    custom-made
  • Application Notes
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The buffer composition is at the discretion of the manufacturer.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C.
    Expiry Date
    12 months
  • Target
    MON1A (MON1 Homolog A (MON1A))
    Alternative Name
    Mon1a (MON1A Products)
    Background
    Vacuolar fusion protein MON1 homolog A,FUNCTION: Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (PubMed:17632513). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (By similarity). {ECO:0000250|UniProtKB:Q86VX9, ECO:0000269|PubMed:17632513}.
    Molecular Weight
    62.1 kDa
    UniProt
    Q6PDG8
    Pathways
    Transition Metal Ion Homeostasis
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