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LAX1 Protein (AA 1-407) (His tag)

custom-made LAX1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7558623
  • Target See all LAX1 Proteins
    LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-407
    Origin
    • 3
    • 1
    Mouse
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LAX1 protein is labelled with His tag.
    Purpose
    Custom-made recombinant Lax1 Protein expressed in mammalian cells.
    Sequence
    MYSTPAPPEV TRRNSEPSTR QGTLGSLQGE KGQIIFPGFV VLLTIILVII AACILWSWKK QKKRPVPYFQ VAPSLTLPPP RHRAKNIYDF LPRQQTELGR HQLSGFSTES LLSRASDSPE PEAPQANGSL QMHRVSVHTV EYSVNIYDNG TVPQMCRHLA SSTHHVCVRT SRSNPSISSK ESNDYVNIPT VEDTCETLTR IESTPENHLG LPSALRLEFA EGGHAGCGNA TDHDGFWAPG PKCSDSLSDG DDLSQTSNDY VNMTGLDLEN IQENRPRGAF QCCRDYENVP WVDTNESQLP TLEEVASSTV DHREPVWRTL SSVYHMAFQP SAQSEDSAMV HREEQSSEDS SDYETVLVAE LEGRDWKQGP GTQHPSDEGT PGDLAGKLCE VVYPAGSLAT ETSDEDA Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    Specificity
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    Characteristics
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    Purity
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    Grade
    custom-made
    Top Product
    Discover our top product LAX1 Protein
  • Application Notes
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The buffer composition is at the discretion of the manufacturer.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C.
    Expiry Date
    12 months
  • Target
    LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))
    Alternative Name
    Lax1 (LAX1 Products)
    Background
    Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX),FUNCTION: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. {ECO:0000269|PubMed:15843560}.
    Molecular Weight
    44.8 kDa
    UniProt
    Q8BHB3
    Pathways
    Production of Molecular Mediator of Immune Response
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