TRMT6 Protein (AA 1-497) (His tag)

Catalog No. ABIN7559280

Product Details

Target: TRMT6 (tRNA Methyltransferase 6 Homolog (TRMT6))

Protein Type: Recombinant

Protein Characteristics: AA 1-497

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This TRMT6 protein is labelled with His tag.

Purpose: Custom-made recombinant Trmt6 Protein expressed in mammalian cells.

Sequence: MEASAAEQPS SPPPPLGDHC IHDGDFVVLK REDVFKAVQV QRRKKVTFEK QWFYLDNAIG HSYGSAFDVS SGGSLQLRKK LEEPASETKE AGTDNRNIVD DGKSQKLTQD DIKALKDKGI KGEEIVQQLI ENSTTFRDKT EFAQDKYIKK KKKKYEAIVT ILKPSTRILS IMYYAREPGK INHMRYDTLA QMLTLGNIRA GNKMIVMETC SGLVLGAMME RMGGFGSIIQ LYPGDGPVRA ATACFGFPKS FLSGLYEFPL NKVNSLLNGT FSAEMLSSEP KDSTPVEESN GELEEKEIAE QADEDNIVDA AENNSGEQRP MEIVPGDPEN KEPKEKRSKR DYIQEKQRRQ EEQRKRHLEA AALLGERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVV SDSLRADPSL KSCTGALDPH KAEEPAAKKQ KCMESAS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Specificity: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Characteristics: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Purity: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Grade: custom-made

Application Details

Application Notes: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -80 °C

Storage Comment: Store at -80°C.

Expiry Date: 12 months

Target Details

Target: TRMT6 (tRNA Methyltransferase 6 Homolog (TRMT6))

Alternative Name: Trmt6 (TRMT6 Products)

Background: TRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6) (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6),FUNCTION: Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. {ECO:0000250|UniProtKB:Q9UJA5}.

Molecular Weight: 55.5 kDa

UniProt: Q8CE96

AlphaFold: Q8CE96