PHF13 Protein (AA 1-296) (His tag)
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- Target See all PHF13 Proteins
- PHF13 (PHD Finger Protein 13 (PHF13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-296
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PHF13 protein is labelled with His tag.
- Purpose
- Made-to-order recombinant Phf13 Protein expressed in mammalian cells.
- Sequence
- MDSDSCAAAF HPEEYSPTCK RRRTVEDFNK FCTFVLAYAG YIPYPKEELP LRSSPSPANS TAGTIDSDGW DTGFSDITPS VPDRCFSHLQ PSLLQRAKPS NYLLDRKTTD KLKKKKRRKR RDSDIPVKEG FRESLLKLEA ADPYVETPSS PTMQDIPQAS ADPCSGWDSD TPSSGSCATV SPDQVTEIKT EGKRTIVRQG KQVVFRDEDS TGNDEDIMVD SDDDSWDLVT CFCMKPFAGR PMIECNECHT WIHLSCAKIR KSNVPEVFVC QKCRDSKFDI RRSNRSRMGS RKLFLD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product PHF13 Protein
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PHD Finger Protein 13 (PHF13) (AA 1-300) protein (His tag)
custom-made PHF13 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PHD Finger Protein 13 (PHF13) (AA 1-300) protein (His tag)PHF13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- PHF13 (PHD Finger Protein 13 (PHF13))
- Alternative Name
- Phf13 (PHF13 Products)
- Background
- PHD finger protein 13,FUNCTION: Modulates chromatin structure and DNA damage response by regulating key determinants of chromatin compaction and DNA damage response. Binds H3K4me3-containing chromatin and promotes DNA condensation by recruiting corepressors such as TRIM28 and H3K9 methyltransferase SETDB1. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. Increases both chromatin-associated levels and activity of H3K9 methyltransferases, such as SETDB1, thus enhancing H3K9 trimethylation (By similarity). Essential for testicular stem-cell differentiation and sustained spermatogenesis (PubMed:21852425). {ECO:0000250|UniProtKB:Q86YI8, ECO:0000269|PubMed:21852425}.
- Molecular Weight
- 33.4 kDa
- UniProt
- Q8K2W6
- AlphaFold
- Q8K2W6
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