TMEM203 Protein (AA 1-136) (His tag)
custom-made
TMEM203
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all TMEM203 products
- TMEM203 (Transmembrane Protein 203 (TMEM203))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-136
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TMEM203 protein is labelled with His tag.
- Purpose
- Custom-made recombinant Tmem203 Protein expressed in mammalian cells.
- Sequence
- MLFSLRELVQ WLGFATFEIF VHLLALLVFS VLLALRVDGL TPGLSWWNVF VPFFAADGLS TYFTTIVSVR LFQDGEKRLA VLRLFWVLTV LSLKFVFEML LCQKLVEQTR ELWFGLITSP VFILLQLLMI RACRVN Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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Transmembrane Protein 203 (TMEM203) (AA 1-136) protein (His tag)
custom-made TMEM203 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- TMEM203 (Transmembrane Protein 203 (TMEM203))
- Alternative Name
- Tmem203 (TMEM203 Products)
- Background
- Transmembrane protein 203,FUNCTION: Involved in the regulation of cellular calcium homeotasis (PubMed:25996873). Required for spermatogenesis (PubMed:25996873). Acts as a regulator of STING-mediated inflammatory signaling in macrophages (PubMed:31346090). Forms a complex with STING, promoting the activity of TBK1 kinase and the transcription factor IRF3, leading to activation of type I interferon expression (PubMed:31346090). {ECO:0000269|PubMed:25996873, ECO:0000269|PubMed:31346090}.
- Molecular Weight
- 15.8 kDa
- UniProt
- Q8R235
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