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Tmc2 Protein (AA 1-888) (His tag)

custom-made Tmc2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7559764
  • Target See all Tmc2 Proteins
    Tmc2 (Transmembrane Channel-Like 2 (Tmc2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-888
    Origin
    • 2
    • 1
    Mouse
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Tmc2 protein is labelled with His tag.
    Purpose
    Custom-made recombinant Tmc2 Protein expressed in mammalian cells.
    Sequence
    MSPQLKSLDE EGDKSARRPT RKQTSRAACP QDGHRAQSSR KDPAKGSPRP GSSRKKQMEH GSYHKGLQGQ KPRKVERSLQ GRKKDRRTSL KEQRASPKKE REALRKEAGK QLRKPRSTSL GSSVSTGDSL SEEELAQILE QVEEKKKLIT TVRNKPWPMA KKLRELREAQ AFVEKYEGAL GKGKGKHLYA YRMMMAKKWV KFKRDFDNFK TQCIPWEMKI KDIESHFGSS VASYFIFLRW MYGVNLVLFG LIFGLVIIPE VLMGMPYGSI PRKTVPRAEE ERAMDFSVLW DFEGYIKYSA LFYGYYNNQR TIGWLRYRLP MAYFMVGVSV FGYSLMIVIR SMASNTQGST SEGDSDSFTF SFKMFTSWDY LIGNSETADN KYVSITTSFK ESIVDEQESN KEGNIHLTRF LRVLANFLIL CCLCGSGYLI YFVVKRSQEF SKMQNVSWYE RNEVEIVMSL LGMFCPPLFE TIAALENYHP RTGLKWQLGR IFALFLGNLY TFLLALMDDV HLKLSNEEKI KNITHWTLFN YYNSSGGNES VPRPPPHPAD VPRGSCWETA VGIEFMRLTV SDMLVTYLTI LVGDFLRACF VRFMNHCWCW DLEAGFPSYA EFDISGNVLG LIFNQGMIWM GSFYAPGLVG INVLRLLTSM YFQCWAVMSS NVPHERVFKA SRSNNFYMGL LLLVLFLSLL PVAYTVMSLP PSFDCGPFSG KNRMYDVLHE TIENDFPKFL GKIFAFLANP GLIIPAILLM FLAIYYLNSV SKSLSRANAQ LRKKIQALRE VEKNHKSIKG KAIVTYSEDT IKNSSKNATQ IHLTKEEPTS HSSSQIQTLD KKAQGPHTSS TEGGASPSTS WHHVGSQPPR GRRDSGQPQS QTYTGRSPSG KRTQRPHN Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    Specificity
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    Characteristics
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    Purity
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    Grade
    custom-made
    Top Product
    Discover our top product Tmc2 Protein
  • Application Notes
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The buffer composition is at the discretion of the manufacturer.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C.
    Expiry Date
    12 months
  • Target
    Tmc2 (Transmembrane Channel-Like 2 (Tmc2))
    Alternative Name
    Tmc2 (Tmc2 Products)
    Background
    Transmembrane channel-like protein 2 (Transmembrane cochlear-expressed protein 2),FUNCTION: Probable ion channel required for the normal function of cochlear hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery. Involved in mechanosensitive responses of the hair cells (By similarity). {ECO:0000250|UniProtKB:E7FFT2, ECO:0000250|UniProtKB:Q8TDI7}.
    Molecular Weight
    101.1 kDa
    UniProt
    Q8R4P4
    AlphaFold
    Q8R4P4
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