CDCA7L Protein (AA 1-438) (His tag)
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- Target See all CDCA7L Proteins
- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-438
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDCA7L protein is labelled with His tag.
- Purpose
- Custom-made recombinant Cdca7l Protein expressed in mammalian cells.
- Sequence
- MELATRSQIP KEVADIFSAP SDDEEFVGFQ DDVPMQNLSE SCGSLDSREL EKQQNVCFRS KYFTEELRRI FKEDTDSEME DFEGFTESEL NMSSNPELME SELSDSDKAY PVMNDAEEDD EEEAAPRRGR STRRSSFGLR VAFQFPTKKL ARTPDKDSSH LLDSKTDLRR KKSSRQPKGK EDSASDAEDE SRAESQENSD ALLKRAMNIK ENKAMLAQLL AELNSVPDFF PVRTPPSASR RRTPRRAFSE GQITRRMNPT RSARPPEKFA LENFTFSATK LTEELYSFRR RKTISGGKCQ TYRRHRISSF RSVKDITEED LENIAITVRD KVYDKVLGNT CHQCRQKTID TKTVCRNQSC GGVRGQFCGP CLRNRYGEDV RTALLDPKWT CPPCRGICNC SYCRRRDGRC ATGILIHLAK FYGYDNVKEY LESLQKQL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
- Top Product
- Discover our top product CDCA7L Protein
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
- Alternative Name
- Cdca7l (CDCA7L Products)
- Background
- Cell division cycle-associated 7-like protein (Transcription factor RAM2),FUNCTION: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells (By similarity). Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. {ECO:0000250, ECO:0000269|PubMed:16829576}.
- Molecular Weight
- 50.2 kDa
- UniProt
- Q922M5
- AlphaFold
- Q922M5
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